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Probing glycine receptor stoichiometry in superficial dorsal horn neurones using the spasmodic mouse
ABSTRACT: Inhibitory glycine receptors (GlyRs) are pentameric ligand gated ion channels composed of α and β subunits assembled in a 2:3 stoichiometry. The α1/β heteromer is considered the dominant GlyR isoform at ‘native’ adult synapses in the spinal cord and brainstem. However, the α3 GlyR subunit...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Blackwell Science Inc
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3115819/ https://ncbi.nlm.nih.gov/pubmed/21486794 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2011.206326 |
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