Probing glycine receptor stoichiometry in superficial dorsal horn neurones using the spasmodic mouse

ABSTRACT: Inhibitory glycine receptors (GlyRs) are pentameric ligand gated ion channels composed of α and β subunits assembled in a 2:3 stoichiometry. The α1/β heteromer is considered the dominant GlyR isoform at ‘native’ adult synapses in the spinal cord and brainstem. However, the α3 GlyR subunit...

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Bibliographische Detailangaben
Hauptverfasser: Graham, B A, Tadros, M A, Schofield, P R, Callister, R J
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 2011
Schlagworte:
Neuroscience
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115819/
https://ncbi.nlm.nih.gov/pubmed/21486794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2011.206326
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