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Effects of T-state and R-state stabilization on deoxyhemoglobin-nitrite reactions and stimulation of nitric oxide signaling

Recent data suggest that transitions between the relaxed (R) and tense (T) state of hemoglobin control the reduction of nitrite to nitric oxide (NO) by deoxyhemoglobin. This reaction may play a role in physiologic NO homeostasis and be a novel consideration for the development of the next generation...

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Detalhes bibliográficos
Main Authors: Cantu-Medellin, Nadiezhda, Vitturi, Dario A., Rodriguez, Cilina, Murphy, Serena, Dorman, Scott, Shiva, Sruti, Zhou, Yipin, Jia, Yiping, Palmer, Andre F., Patel, Rakesh P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115472/
https://ncbi.nlm.nih.gov/pubmed/21277987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.niox.2011.01.006
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