Sodium nitrite therapy attenuates hypertensive effects of HBOC-201 via nitrite reduction

Hypertension secondary to scavenging of nitric oxide (NO) remains a limitation in the use hemoglobin based oxygen carriers (HBOCs). Recent studies suggest that nitrite reduction to NO by deoxyhemoglobin supports NO-signaling. Herein, we tested whether nitrite would attenuate HBOC-mediated hypertensi...

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Main Authors: Rodriguez, Cilina, Vitturi, Dario A., He, Jin, Vandromme, Marianne, Brandon, Angela, Hutchings, Anne, Rue, Loring W., Kerby, Jeffrey D, Patel, Rakesh P.
Format: Artigo
Jezik:Inglês
Izdano: 2009
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775055/
https://ncbi.nlm.nih.gov/pubmed/19555351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20090735
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