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Pentoxifylline Enhances the Radioprotective Properties of γ-Tocotrienol: Differential Effects on the Hematopoietic, Gastrointestinal and Vascular Systems

The vitamin E analog γ-tocotrienol (GT3) is a potent radioprotector and mitigator. This study was performed to (a) determine whether the efficacy of GT3 can be enhanced by the addition of the phosphodiesterase inhibitor pentoxifylline (PTX) and (b) to obtain information about the mechanism of action...

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Bibliographic Details
Main Authors: Berbée, Maaike, Fu, Qiang, Garg, Sarita, Kulkarni, Shilpa, Kumar, K. Sree, Hauer-Jensen, Martin
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115470/
https://ncbi.nlm.nih.gov/pubmed/21388273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR2399.1
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