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Identification of new Gβγ interaction sites in adenylyl cyclase 2
The role of Gβγ in adenylyl cyclase (AC) signaling is complicated due to its role as a conditional activator (AC2, AC4 and AC7) and an inhibitor (AC1, AC3 and AC8). AC2 is stimulated by Gα(s) and if Gβγ is present the stimulation is synergistic. The precise mechanism of this synergistic activation i...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3115457/ https://ncbi.nlm.nih.gov/pubmed/21596131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2011.05.002 |
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