Structural Characterization of the Mitomycin 7-O-Methyltransferase MmcR

Mitomycins are quinone-containing antibiotics, widely used as anti-tumor drugs in chemotherapy. Mitomycin-7-O-methyltransferase (MmcR), a key tailoring enzyme involved in the biosynthesis of mitomycin in Streptomyces lavendulae, catalyzes the 7-O-methylation of both C9β- and C9α-configured 7-hydroxy...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Singh, Shanteri, Chang, Aram, Goff, Randal D., Bingman, Craig A., Grüschow, Sabine, Sherman, David H., Phillips, George N., Thorson, Jon S.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115387/
https://ncbi.nlm.nih.gov/pubmed/21538548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.23040
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker