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Segregation of point mutation heteroplasmy in the control region of dog mtDNA studied systematically in deep generation pedigrees

Heteroplasmy, the presence of two or more variants in an organism, may render mitochondrial DNA (mtDNA)-based individual identification challenging in forensic analysis. However, the variation of heteroplasmic proportions and the segregation of heteroplasmic variants through generations and within f...

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Main Authors: Klütsch, Cornelya F. C., Seppälä, Eija H., Uhlén, Mathias, Lohi, Hannes, Savolainen, Peter
Formato: Artigo
Idioma:Inglês
Publicado: Springer-Verlag 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115052/
https://ncbi.nlm.nih.gov/pubmed/21049272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00414-010-0524-7
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