Detecting copy number status and uncovering subclonal markers in heterogeneous tumor biopsies

BACKGROUND: Genomic aberrations can be used to determine cancer diagnosis and prognosis. Clinically relevant novel aberrations can be discovered using high-throughput assays such as Single Nucleotide Polymorphism (SNP) arrays and next-generation sequencing, which typically provide aggregate signals...

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Bibliografiske detaljer
Main Authors: Parisi, Fabio, Ariyan, Stephan, Narayan, Deepak, Bacchiocchi, Antonella, Hoyt, Kathleen, Cheng, Elaine, Xu, Fang, Li, Peining, Halaban, Ruth, Kluger, Yuval
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3114747/
https://ncbi.nlm.nih.gov/pubmed/21569352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-12-230
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