Bioanalytical Screening of Riboflavin Antagonists for Targeted Drug Delivery—A Thermodynamic and Kinetic Study

[Image: see text] The present study screened riboflavin mimicking small molecules to determine their binding activity for the riboflavin binding protein. We performed thermodynamic and kinetic binding studies of these molecules using a combination of two analytical approaches: isothermal titration c...

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Bibliografiske detaljer
Main Authors: Plantinga, Anna, Witte, Amanda, Li, Ming-Hsin, Harmon, Andrew, Choi, Seok Ki, Banaszak Holl, Mark M., Orr, Bradford G., Baker, James R., Sinniah, Kumar
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2011
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3114641/
https://ncbi.nlm.nih.gov/pubmed/21686082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml100296z
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