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Transcriptional regulation of bone morphogenetic protein 4 by tumor necrosis factor and its relationship with age-related macular degeneration

Bone morphogenetic protein-4 (BMP4) may be involved in the molecular switch that determines which late form of age-related macular degeneration (AMD) an individual develops. BMP4 expression is high in retinal pigment epithelium (RPE) cells in late, dry AMD patients, while BMP4 expression is low in t...

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書誌詳細
主要な著者: Xu, Jing, Zhu, Danhong, He, Shikun, Spee, Christine, Ryan, Stephen J., Hinton, David R.
フォーマット: Artigo
言語:Inglês
出版事項: Federation of American Societies for Experimental Biology 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3114537/
https://ncbi.nlm.nih.gov/pubmed/21411747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.10-178350
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