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Viral envelope protein folding and membrane hemifusion are enhanced by the conserved loop region of HIV-1 gp41

Fusion of human immunodeficiency virus (HIV-1) with target cells is mediated by the gp41 transmembrane envelope protein. The loop region within gp41 contains 2 crucial cysteines that play an unknown role in HIV-cell fusion. On the basis of cell-cell fusion assay, using human T-cell lines [Jurkat E6-...

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Hlavní autoři: Ashkenazi, Avraham, Viard, Mathias, Wexler-Cohen, Yael, Blumenthal, Robert, Shai, Yechiel
Médium: Artigo
Jazyk:Inglês
Vydáno: Federation of American Societies for Experimental Biology 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3114521/
https://ncbi.nlm.nih.gov/pubmed/21429941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.10-175752
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