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Sphingopeptides: dihydrosphingosine‐based fusion inhibitors against wild‐type and enfuvirtide‐resistant HIV‐1

Understanding the structural organization of lipids in the cell and viral membranes is essential for elucidating mechanisms of viral fusion that lead to entry of enveloped viruses into their host cells. The HIV lipidome shows a remarkable enrichment in dihydrosphingomyelin, an unusual sphingolipid f...

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Detalhes bibliográficos
Main Authors: Ashkenazi, Avraham, Viard, Mathias, Unger, Linor, Blumenthal, Robert, Shai, Yechiel
Formato: Artigo
Idioma:Inglês
Publicado em: The Federation of American Societies for Experimental Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475257/
https://ncbi.nlm.nih.gov/pubmed/22872679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-215111
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