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Strong linkage disequilibrium of a HbE variant with the (AT)(9)(T)(5) repeat in the BP1 binding site upstream of the β-globin gene in the Thai population
A binding site for the repressor protein BP1, which contains a tandem (AT)(x)(T)(y) repeat, is located approximately 530 bp 5′ to the human β-globin gene (HBB). There is accumulating evidence that BP1 binds to the (AT)(9)(T)(5) allele more strongly than to other alleles, thereby reducing the express...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2004
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3114417/ https://ncbi.nlm.nih.gov/pubmed/15551156 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10038-004-0210-z |
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