Altered Skeletal Muscle Lipase Expression and Activity Contribute to Insulin Resistance in Humans

OBJECTIVE: Insulin resistance is associated with elevated content of skeletal muscle lipids, including triacylglycerols (TAGs) and diacylglycerols (DAGs). DAGs are by-products of lipolysis consecutive to TAG hydrolysis by adipose triglyceride lipase (ATGL) and are subsequently hydrolyzed by hormone-...

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Détails bibliographiques
Auteurs principaux: Badin, Pierre-Marie, Louche, Katie, Mairal, Aline, Liebisch, Gerhard, Schmitz, Gerd, Rustan, Arild C., Smith, Steven R., Langin, Dominique, Moro, Cedric
Format: Artigo
Langue:Inglês
Publié: American Diabetes Association 2011
Sujets:
Pathophysiology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3114384/
https://ncbi.nlm.nih.gov/pubmed/21498783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-1364
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