Perilipin 5 fine-tunes lipid oxidation to metabolic demand and protects against lipotoxicity in skeletal muscle

Lipid droplets (LD) play a central role in lipid homeostasis by controlling transient fatty acid (FA) storage and release from triacylglycerols stores, while preventing high levels of cellular toxic lipids. This crucial function in oxidative tissues is altered in obesity and type 2 diabetes. Perilip...

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Vydáno v:Sci Rep
Hlavní autoři: Laurens, Claire, Bourlier, Virginie, Mairal, Aline, Louche, Katie, Badin, Pierre-Marie, Mouisel, Etienne, Montagner, Alexandra, Marette, André, Tremblay, Angelo, Weisnagel, John S., Guillou, Hervé, Langin, Dominique, Joanisse, Denis R., Moro, Cedric
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5138838/
https://ncbi.nlm.nih.gov/pubmed/27922115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38310
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