Perilipin 5 fine-tunes lipid oxidation to metabolic demand and protects against lipotoxicity in skeletal muscle

Lipid droplets (LD) play a central role in lipid homeostasis by controlling transient fatty acid (FA) storage and release from triacylglycerols stores, while preventing high levels of cellular toxic lipids. This crucial function in oxidative tissues is altered in obesity and type 2 diabetes. Perilip...

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Udgivet i:Sci Rep
Main Authors: Laurens, Claire, Bourlier, Virginie, Mairal, Aline, Louche, Katie, Badin, Pierre-Marie, Mouisel, Etienne, Montagner, Alexandra, Marette, André, Tremblay, Angelo, Weisnagel, John S., Guillou, Hervé, Langin, Dominique, Joanisse, Denis R., Moro, Cedric
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5138838/
https://ncbi.nlm.nih.gov/pubmed/27922115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38310
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