Perilipin 5 fine-tunes lipid oxidation to metabolic demand and protects against lipotoxicity in skeletal muscle

Lipid droplets (LD) play a central role in lipid homeostasis by controlling transient fatty acid (FA) storage and release from triacylglycerols stores, while preventing high levels of cellular toxic lipids. This crucial function in oxidative tissues is altered in obesity and type 2 diabetes. Perilip...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Laurens, Claire, Bourlier, Virginie, Mairal, Aline, Louche, Katie, Badin, Pierre-Marie, Mouisel, Etienne, Montagner, Alexandra, Marette, André, Tremblay, Angelo, Weisnagel, John S., Guillou, Hervé, Langin, Dominique, Joanisse, Denis R., Moro, Cedric
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5138838/
https://ncbi.nlm.nih.gov/pubmed/27922115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38310
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