ALDH Activity Selectively Defines an Enhanced Tumor-Initiating Cell Population Relative to CD133 Expression in Human Pancreatic Adenocarcinoma

BACKGROUND: Multiple studies in recent years have identified highly tumorigenic populations of cells that drive tumor formation. These cancer stem cells (CSCs), or tumor-initiating cells (TICs), exhibit properties of normal stem cells and are associated with resistance to current therapies. As pancr...

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Bibliografiske detaljer
Main Authors: Kim, Michael P., Fleming, Jason B., Wang, Huamin, Abbruzzese, James L., Choi, Woonyoung, Kopetz, Scott, McConkey, David J., Evans, Douglas B., Gallick, Gary E.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3113804/
https://ncbi.nlm.nih.gov/pubmed/21695188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020636
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