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A yeast model for polyalanine-expansion aggregation and toxicity
Nine human disorders result from the toxic accumulation and aggregation of proteins with expansions in their endogenous polyalanine (polyA) tracts. Given the prevalence of polyA tracts in eukaryotic proteomes, we wanted to understand the generality of polyA-expansion cytotoxicity by using yeast as a...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3113764/ https://ncbi.nlm.nih.gov/pubmed/21508314 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-01-0037 |
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