Increased ER–mitochondrial coupling promotes mitochondrial respiration and bioenergetics during early phases of ER stress

Increasing evidence indicates that endoplasmic reticulum (ER) stress activates the adaptive unfolded protein response (UPR), but that beyond a certain degree of ER damage, this response triggers apoptotic pathways. The general mechanisms of the UPR and its apoptotic pathways are well characterized....

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Bibliografiske detaljer
Main Authors: Bravo, Roberto, Vicencio, Jose Miguel, Parra, Valentina, Troncoso, Rodrigo, Munoz, Juan Pablo, Bui, Michael, Quiroga, Clara, Rodriguez, Andrea E., Verdejo, Hugo E., Ferreira, Jorge, Iglewski, Myriam, Chiong, Mario, Simmen, Thomas, Zorzano, Antonio, Hill, Joseph A., Rothermel, Beverly A., Szabadkai, Gyorgy, Lavandero, Sergio
Format: Artigo
Sprog:Inglês
Udgivet: Company of Biologists 2011
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3113668/
https://ncbi.nlm.nih.gov/pubmed/21628424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.080762
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