Increased ER–mitochondrial coupling promotes mitochondrial respiration and bioenergetics during early phases of ER stress

Increasing evidence indicates that endoplasmic reticulum (ER) stress activates the adaptive unfolded protein response (UPR), but that beyond a certain degree of ER damage, this response triggers apoptotic pathways. The general mechanisms of the UPR and its apoptotic pathways are well characterized....

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Detalhes bibliográficos
Main Authors: Bravo, Roberto, Vicencio, Jose Miguel, Parra, Valentina, Troncoso, Rodrigo, Munoz, Juan Pablo, Bui, Michael, Quiroga, Clara, Rodriguez, Andrea E., Verdejo, Hugo E., Ferreira, Jorge, Iglewski, Myriam, Chiong, Mario, Simmen, Thomas, Zorzano, Antonio, Hill, Joseph A., Rothermel, Beverly A., Szabadkai, Gyorgy, Lavandero, Sergio
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2011
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3113668/
https://ncbi.nlm.nih.gov/pubmed/21628424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.080762
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