Effects of Natural Selection and Gene Conversion on the Evolution of Human Glycophorins Coding for MNS Blood Polymorphisms in Malaria-Endemic African Populations

Malaria has been a very strong selection pressure in recent human evolution, particularly in Africa. Of the one million deaths per year due to malaria, more than 90% are in sub-Saharan Africa, a region with high levels of genetic variation and population substructure. However, there have been few st...

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Huvudupphovsmän: Ko, Wen-Ya, Kaercher, Kristin A., Giombini, Emanuela, Marcatili, Paolo, Froment, Alain, Ibrahim, Muntaser, Lema, Godfrey, Nyambo, Thomas B., Omar, Sabah A., Wambebe, Charles, Ranciaro, Alessia, Hirbo, Jibril B., Tishkoff, Sarah A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2011
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3113242/
https://ncbi.nlm.nih.gov/pubmed/21664997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2011.05.005
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