Identifying Darwinian Selection Acting on Different Human APOL1 Variants among Diverse African Populations

Disease susceptibility can arise as a consequence of adaptation to infectious disease. Recent findings have suggested that higher rates of chronic kidney disease (CKD) in individuals with recent African ancestry might be attributed to two risk alleles (G1 and G2) at the serum-resistance-associated (...

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Main Authors: Ko, Wen-Ya, Rajan, Prianka, Gomez, Felicia, Scheinfeldt, Laura, An, Ping, Winkler, Cheryl A., Froment, Alain, Nyambo, Thomas B., Omar, Sabah A., Wambebe, Charles, Ranciaro, Alessia, Hirbo, Jibril B., Tishkoff, Sarah A.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3710747/
https://ncbi.nlm.nih.gov/pubmed/23768513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2013.05.014
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