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Hyperactivity and Learning Deficits in Transgenic Mice Bearing a Human Mutant Thyroid Hormone β1 Receptor Gene

Resistance to thyroid hormone (RTH) is a human syndrome mapped to the thyroid receptor β (TRβ) gene on chromosome 3, representing a mutation of the ligandbinding domain of the TRβ gene. The syndrome is characterized by reduced tissue responsiveness to thyroid hormone and elevated serum levels of thy...

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Publicat a:Learn Mem
Autors principals: McDonald, Michael P., Wong, Rosemary, Goldstein, Gregory, Weintraub, Bruce, Cheng, Sheue-yann, Crawley, Jacqueline N.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 1998
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC311272/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10454355/
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