Highly Elevated Serum Hepcidin in Patients with Acute Myeloid Leukemia prior to and after Allogeneic Hematopoietic Cell Transplantation: Does This Protect from Excessive Parenchymal Iron Loading?

Hepcidin is upregulated by inflammation and iron. Inherited (HFE genotype) and treatment-related factors (blood units (BU), Iron overload) affecting hepcidin (measured by C-ELISA) were studied in 42 consecutive patients with AML prior to and after allogeneic hematopoietic cell transplantation (HCT)....

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Autori principali: Eisfeld, Ann-Kathrin, Westerman, Mark, Krahl, Rainer, Leiblein, Sabine, Liebert, Uwe Gerd, Hehme, Marianne, Teupser, Daniel, Niederwieser, Dietger, Al-Ali, Haifa Kathrin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3112503/
https://ncbi.nlm.nih.gov/pubmed/21687645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/491058
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