Novel Cell- and Tissue-Based Assays for Detecting Misfolded and Aggregated Protein Accumulation Within Aggresomes and Inclusion Bodies

Aggresomes and related inclusion bodies appear to serve as storage depots for misfolded and aggregated proteins within cells, which can potentially be degraded by the autophagy pathway. A homogenous fluorescence-based assay was devised to detect aggregated proteins inside aggresomes and inclusion bo...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Shen, Dee, Coleman, Jack, Chan, Eric, Nicholson, Thomas P., Dai, Lijun, Sheppard, Paul W., Patton, Wayne F.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Humana Press Inc 2010
Gaiak:
Original Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3112480/
https://ncbi.nlm.nih.gov/pubmed/21132543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12013-010-9138-4
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