Induction of latency-associated peptide (transforming growth factor-β(1)) expression on CD4(+) T cells reduces Toll-like receptor 4 ligand-induced tumour necrosis factor-α production in a transforming growth factor-β-dependent manner

CD4(+) T cells expressing the latent form of transforming growth factor-β [latency-associated peptide (LAP) (TGF-β(1))] play an important role in the modulation of immune responses. Here, we identified a novel peptide ligand (GPC(81–95)) with an intrinsic ability to induce membrane-bound LAP (TGF-β(...

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Main Authors: Boswell, Sandra, Sharif, Shayan, Alisa, Akeel, Pereira, Stephen P, Williams, Roger, Behboudi, Shahriar
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2011
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3112337/
https://ncbi.nlm.nih.gov/pubmed/21426338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2011.03425.x
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