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Pilot Study Evaluating the Interaction Between Paclitaxel and Protease Inhibitors in Patients with Human Immunodeficiency Virus-Associated Kaposi’s Sarcoma: An Eastern Cooperative Oncology Group (ECOG) and AIDS Malignancy Consortium (AMC) Trial
PURPOSE: Paclitaxel, a cytotoxic agent metabolized by cytochrome P450 hepatic enzymes, is active for the treatment of human immunodeficiency (HIV) associated Kaposi’s sarcoma. Protease inhibitors are commonly used to treat HIV infection and are known to inhibit cytochrome P450. We sought to determin...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3112249/ https://ncbi.nlm.nih.gov/pubmed/21207228 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-010-1509-4 |
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