Phase II Trial of Imatinib in AIDS-Associated Kaposi's Sarcoma: AIDS Malignancy Consortium Protocol 042

PURPOSE: Kaposi's sarcoma (KS) is a disease of multifocal vascular proliferation that requires infection with KS herpes virus (KSHV/HHV-8). Activation of the c-kit and platelet-derived growth factor (PDGF) receptors by autocrine/paracrine mechanisms follows endothelial cell KSHV infection. In a...

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Autori principali: Koon, Henry B., Krown, Susan E., Lee, Jeannette Y., Honda, Kord, Rapisuwon, Suthee, Wang, Zhenghe, Aboulafia, David, Reid, Erin G., Rudek, Michelle A., Dezube, Bruce J., Noy, Ariela
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Clinical Oncology 2014
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ORIGINAL REPORTS
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3912327/
https://ncbi.nlm.nih.gov/pubmed/24378417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2012.48.6365
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