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GRISOTTO: A greedy approach to improve combinatorial algorithms for motif discovery with prior knowledge

BACKGROUND: Position-specific priors (PSP) have been used with success to boost EM and Gibbs sampler-based motif discovery algorithms. PSP information has been computed from different sources, including orthologous conservation, DNA duplex stability, and nucleosome positioning. The use of prior info...

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Detalhes bibliográficos
Main Authors: Carvalho, Alexandra M, Oliveira, Arlindo L
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3112114/
https://ncbi.nlm.nih.gov/pubmed/21513505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-7188-6-13
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