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Allosteric crosstalk between peptide-binding, transport, and ATP hydrolysis of the ABC transporter TAP
The transporter associated with antigen processing (TAP) is essential for intracellular transport of protein fragments into the endoplasmic reticulum for loading of major histocompatibility complex (MHC) class I molecules. On the cell surface, these peptide–MHC complexes are monitored by cytotoxic T...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The National Academy of Sciences
2001
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC31121/ https://ncbi.nlm.nih.gov/pubmed/11274390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.061467898 |
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