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Induction of human fetal hemoglobin via the NRF2 antioxidant response signaling pathway
Although hematopoietic stem cell transplantation and gene therapy have the potential to cure β-thalassemia and sickle cell disease, they are not currently available to most people with these diseases. In the near term, pharmacologic induction of fetal hemoglobin (HbF) may offer the best possibility...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society of Hematology
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3112042/ https://ncbi.nlm.nih.gov/pubmed/21464371 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-10-314096 |
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