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The interaction between the iron-responsive element binding protein and its cognate RNA is highly dependent upon both RNA sequence and structure.

To assess the influence of RNA sequence/structure on the interaction RNAs with the iron-responsive element binding protein (IRE-BP), twenty eight altered RNAs were tested as competitors for an RNA corresponding to the ferritin H chain IRE. All changes in the loop of the predicted IRE hairpin and in...

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Autori principali: Jaffrey, S R, Haile, D J, Klausner, R D, Harford, J B
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1993
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC311201/
https://ncbi.nlm.nih.gov/pubmed/8233801
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