A novel method for the determination of post-transcriptional modification in RNA by mass spectrometry.
A method is described for the detection, chemical characterization and sequence placement of post-transcriptionally modified nucleotides in RNA. Molecular masses of oligonucleotides produced by RNase T1 hydrolysis can be measured by electrospray mass spectrometry with errors of less than 1 Da, which...
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| Publicado en: | Nucleic Acids Res |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
1993
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| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC311193/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8233793/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/21.19.4577 |
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