Base composition analysis of oligonucleotides containing apurinic sites.

Upon base composition analysis, oligonucleotides which are labeled at the 3'-terminus with fluorescein or biotin generate an additional, late eluting peak in the HPLC chromatogram. Investigation of this effect revealed the haptens acted as apurinic sites, and phosphodiesterase cleavage of the phosph...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Morgan, R L, Celebuski, J E, Fino, J R
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1993
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC311192/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8233792/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/21.19.4574
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