HAPPY mapping of a YAC reveals alternative haplotypes in the human immunoglobulin VH locus.
We have identified and sequenced 14 human immunoglobulin VH segments cloned in a yeast artificial chromosome, and have used a rapid PCR-based technique (HAPPY mapping, 12) to derive the order and approximate distances between them. The sequences mapped comprise thirteen germline VH segments and one...
Uloženo v:
| Vydáno v: | Nucleic Acids Res |
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| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
1993
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| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC311185/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8233786/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/21.19.4524 |
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