HAPPY mapping of a YAC reveals alternative haplotypes in the human immunoglobulin VH locus.

We have identified and sequenced 14 human immunoglobulin VH segments cloned in a yeast artificial chromosome, and have used a rapid PCR-based technique (HAPPY mapping, 12) to derive the order and approximate distances between them. The sequences mapped comprise thirteen germline VH segments and one...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Walter, G, Tomlinson, I M, Cook, G P, Winter, G, Rabbitts, T H, Dear, P H
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1993
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC311185/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8233786/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/21.19.4524
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