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Peptide hybrids containing α- and β-amino acids: Structure of a decapeptide β-hairpin with two facing β-phenylalanine residues

A β-hairpin conformation has been characterized in crystals of the decapeptide t-butoxycarbonyl-Leu-Val-βPhe-Val-(D)Pro-Gly-Leu-βPhe-Val-Val-methyl ester [βPhe; (S)-β(3) homophenylalanine] by x-ray diffraction. The polypeptide chain reversal is nucleated by the centrally positioned (D)Pro-Gly segmen...

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Detalhes bibliográficos
Main Authors: Karle, Isabella L., Gopi, Hosahudya N., Balaram, Padmanabhan
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC31118/
https://ncbi.nlm.nih.gov/pubmed/11259666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.071050198
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