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Hybrid Peptide Hairpins Containing α- and ω-Amino Acids: Conformational Analysis of Decapeptides with Unsubstituted β-, γ-, and δ-Residues at Positions 3 and 8

The effects of inserting un-substituted ω-amino acids into the strand segments of model β-hairpin peptides was investigated by using four synthetic decapeptides, Boc-Leu-Val-Xxx-Val-d-Pro-Gly-Leu-Xxx-Val-Val-OMe: peptide 1 (Xxx=Gly), peptide 2 (Xxx = βGly = βhGly = homoglycine, β-glycine), peptide 3...

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Bibliographische Detailangaben
Hauptverfasser: Roy, Rituparna S., Gopi, Hosahudya N., Raghothama, Srinivasarao, Karle, Isabella L., Balaram, Padmanabhan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1435683/
https://ncbi.nlm.nih.gov/pubmed/16453362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.200500742
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