The 5' flanking sequence negatively modulates the in vivo expression and in vitro transcription of a human tRNA gene.

The consequences of altering the 5' flanking region of a human amber suppressor tRNA(ser) gene on phenotypic expression in vivo and transcription in vitro was examined by constructing a series of upstream deletion and substitution mutants. The resulting tDNA variants were examined for functional tRN...

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Veröffentlicht in:	Nucleic Acids Res
Hauptverfasser:	Tapping, R I, Syroid, D E, Bilan, P T, Capone, J P
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Oxford University Press 1993
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC311178/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8233781/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/21.19.4476
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