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The 5' flanking sequence negatively modulates the in vivo expression and in vitro transcription of a human tRNA gene.
The consequences of altering the 5' flanking region of a human amber suppressor tRNA(ser) gene on phenotypic expression in vivo and transcription in vitro was examined by constructing a series of upstream deletion and substitution mutants. The resulting tDNA variants were examined for functiona...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
1993
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| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC311178/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8233781/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/21.19.4476 |
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