The synthesis of oligoribonucleotides containing O6-methylguanosine: the role of conserved guanosine residues in hammerhead ribozyme cleavage.

The synthesis is described of oligoribonucleotides containing the modified nucleoside O6-methylguanosine. Solid-phase oligoribonucleotide assembly was carried out by use of 2'-silyl-protected nucleoside phosphoramidites, a new O6-methylguanosine-containing synthon and a mild deprotection method. The...

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Vydáno v:	Nucleic Acids Res
Hlavní autoři:	Grasby, J A, Jonathan, P, Butler, G, Gait, M J
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Oxford University Press 1993
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC311174/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8233777/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/21.19.4444
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