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Impaired Proteostasis Contributes to Renal Tubular Dysgenesis

Protein conformational disorders are associated with the appearance, persistence, accumulation, and misprocessing of aberrant proteins in the cell. The etiology of renal tubular dysgenesis (RTD) is linked to mutations in the angiotensin-converting enzyme (ACE). Here, we report the identification of...

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Detalhes bibliográficos
Main Authors: de Oliveira, Rita Machado, Marijanovic, Zrinka, Carvalho, Filipe, Miltényi, Gabriel Miltenberger, Matos, Joana Estevão, Tenreiro, Sandra, Oliveira, Sónia, Enguita, Francisco Javier, Stone, Rosário, Outeiro, Tiago Fleming
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3111453/
https://ncbi.nlm.nih.gov/pubmed/21695262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020854
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