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Empirical evaluations of analytical issues arising from predicting HLA alleles using multiple SNPs
BACKGROUND: Numerous immune-mediated diseases have been associated with the class I and II HLA genes located within the major histocompatibility complex (MHC) consisting of highly polymorphic alleles encoded by the HLA-A, -B, -C, -DRB1, -DQB1 and -DPB1 loci. Genotyping for HLA alleles is complex and...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3111398/ https://ncbi.nlm.nih.gov/pubmed/21518453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-12-39 |
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