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Phosphoproteomic analysis reveals an intrinsic pathway for histone deacetylase 7 regulation that controls cytotoxic T lymphocyte function

The present study reports an unbiased analysis of cytotoxic T cell serine-threonine phosphoproteome using high resolution mass spectrometry. Approximately 2,000 phosphorylations were identified in CTLs of which approximately 450 were controlled by TCR signaling. A significantly overrepresented group...

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Detalhes bibliográficos
Main Authors: Navarro, Maria N., Goebel, Jurgen, Feijoo-Carnero, Carmen, Morrice, Nick, Cantrell, Doreen A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3110993/
https://ncbi.nlm.nih.gov/pubmed/21399638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2008
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