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Targeting the inflammasome and adenosine type-3 receptors improves outcome of antibiotic therapy in murine anthrax

AIM: To establish whether activation of adenosine type-3 receptors (A3Rs) and inhibition of interleukin-1β-induced inflammation is beneficial in combination with antibiotic therapy to increase survival of mice challenged with anthrax spores. METHODS: DBA/2 mice were challenged with Bacillus anthraci...

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Bibliografische gegevens
Hoofdauteurs: Popov, Serguei G, Popova, Taissia G, Kashanchi, Fatah, Bailey, Charles
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Baishideng Publishing Group Co., Limited 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3110900/
https://ncbi.nlm.nih.gov/pubmed/21666812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4331/wjbc.v2.i5.98
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