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Targeting the inflammasome and adenosine type-3 receptors improves outcome of antibiotic therapy in murine anthrax
AIM: To establish whether activation of adenosine type-3 receptors (A3Rs) and inhibition of interleukin-1β-induced inflammation is beneficial in combination with antibiotic therapy to increase survival of mice challenged with anthrax spores. METHODS: DBA/2 mice were challenged with Bacillus anthraci...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Baishideng Publishing Group Co., Limited
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3110900/ https://ncbi.nlm.nih.gov/pubmed/21666812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4331/wjbc.v2.i5.98 |
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