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High tolerance to mutations in a Chlamydia trachomatis peptide deformylase loop

AIM: To determine if and how a loop region in the peptide deformylase (PDF) of Chlamydia trachomatis regulates enzyme function. METHODS: Molecular dynamics simulation was used to study a structural model of the chlamydial PDF (cPDF) and predict the temperature factor per residue for the protein back...

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Autores principales: Oey, Christopher B, Bao, Xiaofeng, Lewis, Christal, Kerrigan, John E, Fan, Huizhou
Formato: Artigo
Lenguaje:Inglês
Publicado: Baishideng Publishing Group Co., Limited 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3110899/
https://ncbi.nlm.nih.gov/pubmed/21666811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4331/wjbc.v2.i5.90
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