Cyclosporine A mediates Pathogenesis of Aggressive Cutaneous Squamous Cell Carcinoma by Augmenting Epithelial-Mesenchymal Transition: Role of TGF-β Signaling Pathway

Organ transplant recipients (OTRs) develop multiple aggressive and metastatic non-melanoma skin cancers (NMSCs). Yet, the underlying mechanism remains elusive. Employing a variety of immune-compromised murine models, immunoblotting, immunohistochemical and immunofluorescence techniques, we show that...

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Detalhes bibliográficos
Main Authors: Walsh, Stephanie B., Xu, Jianmin, Xu, Hui, Kurundkar, Ashish R., Maheshwari, Akhil, Grizzle, William E., Timares, Laura, Huang, Conway C., Kopelovich, Levy, Elmets, Craig A., Athar, Mohammad
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3110643/
https://ncbi.nlm.nih.gov/pubmed/21308804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.20744
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