Frequent genetic abnormalities of the PI3K/AKT pathway in primary ovarian cancer predict patient outcome

Identification and characterization of underlying genetic aberrations could facilitate diagnosis and treatment of ovarian cancer. Copy number analysis using array Comparative Genomic Hybridization (aCGH) on 93 primary ovarian tumors identified PI3K/AKT pathway as the most frequently altered cancer r...

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Detalhes bibliográficos
Main Authors: Huang, Jia, Zhang, Lin, Greshock, Joel, Colligon, Theresa A., Wang, Yan, Ward, Renee, Katsaros, Dionyssios, Lassus, Heini, Butzow, Ralf, Godwin, Andrew K., Testa, Joseph R., Nathanson, Katherine L., Gimotty, Phyllis A., Coukos, George, Weber, Barbara L., Degenhardt, Yan
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3110626/
https://ncbi.nlm.nih.gov/pubmed/21563232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.20883
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