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The curcuminoid CLEFMA selectively induces cell death in H441 lung adenocarcinoma cells via oxidative stress

CLEFMA or 4-[3,5-bis(2-chlorobenzylidene-4-oxo-piperidine-1-yl)-4-oxo-2-butenoic acid] is a curcuminoid being developed as an anticancer drug. We recently reported that it potently inhibits proliferation of various cancer cells. In this project, we investigated the effect of CLEFMA on gene expressio...

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Detalhes bibliográficos
Main Authors: Sahoo, Kaustuv, Dozmorov, Mikhail G., Anant, Shrikant, Awasthi, Vibhudutta
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3110543/
https://ncbi.nlm.nih.gov/pubmed/21181232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-010-9610-4
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