Randomized Trial of Safety and Effectiveness of Chlorproguanil-Dapsone and Lumefantrine-Artemether for Uncomplicated Malaria in Children in The Gambia

BACKGROUND: Chlorproguanil-dapsone (Lapdap), developed as a low-cost antimalarial, was withdrawn in 2008 after concerns about safety in G6PD deficient patients. This trial was conducted in 2004 to evaluate the safety and effectiveness of CD and comparison with artemether-lumefantrine (AL) under cond...

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Główni autorzy: Dunyo, Samuel, Sirugo, Giorgio, Sesay, Sanie, Bisseye, Cyrille, Njie, Fanta, Adiamoh, Majidah, Nwakanma, Davis, Diatta, Mathurin, Janha, Ramatoulie, Sisay Joof, Fatou, Temple, Beth, Snell, Paul, Conway, David, Walton, Robert, Cheung, Yin Bun, Milligan, Paul
Format: Artigo
Język:Inglês
Wydane: Public Library of Science 2011
Hasła przedmiotowe:
Research Article
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3110183/
https://ncbi.nlm.nih.gov/pubmed/21666744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017371
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